Jacques Galipeau, MD
Director, Program for Advanced Cell Therapy (PACT)
Jacques Galipeau, M.D. FRCP(C) is the Don and Marilyn Anderson Professor of Oncology within the Department of Medicine and UW Carbone Comprehensive Cancer Center at the University of Wisconsin in Madison, and is the inaugural Associate Dean for Therapeutics Development at the University of Wisconsin School of Medicine & Public Health
Prior to coming to UW Madison, Dr. Galipeau was at the Winship Cancer Center at Emory University, where he founded the Emory Personalized Immunotherapy Center and launched clinical trials of MSC-based treatments for Crohn’s disease and graft versus host disease (GVHD), a life-threatening complication of bone marrow transplant. Prior to this, he was a faculty member at McGill University in Montreal, Canada. He is an internationally recognized expert in translational development of cell therapies and the sponsor of a series of FDA-sanctioned clinical trials examining the use of autologous marrow-derived mesenchymal stromal cells for immune disorders, including Crohn’s disease and graft vs host disease. Dr. Galipeau has also developed the field of fusion engineered cytokines known as fusokines, as a novel pharmaceutical means of treating immune disorders and cancer. Dr. Galipeau is the director of the University of Wisconsin Advanced Cell Therapy Program whose mission is to develop personalized cell therapies for immune and malignant disorders and to promote and deploy first-in-human clinical trials of UW cell therapy innovations to improve outcomes for children and adults.
Inga Hofmann, MD
Medical Director, Program for Advanced Cell Therapy (PACT)
Dr. Hofmann is an assistant professor of pediatric hematology, oncology and the Director of Pediatric Stem Cell Transplant program at the UW School of Medicine and Public Health (SMPH). She received her MD degree from Albert Ludwigs University of Freiburg, Germany and completed her pediatric residency at the University of California in San Francisco. Dr. Hofmann also completed her clinical fellowship in pediatric hematology and oncology at the Dana-Farber/Boston Children’s Cancer and Blood Disorder Center at Harvard Medical School, and her post-doctoral fellowship in hematopathology and pediatric hematopathology at the Brigham and Women’s Hospital in Boston and Boston Children’s Hospital. At Boston Children’s Hospital, she discovered her passion for cell therapy. She became devoted to the rare childhood bone marrow failure and myelodysplastic syndromes (MDS). Dr.Hofmann created a national registry of patients and their blood samples in the hopes of completing research to help develop treatments for these often fatal diseases.As the Medical Director, Dr. Hofmann manages the interaction between patients, SMPH, American Family Children’s Hospital clinical trials office and PACT as the program manufactures a variety of cell types to conduct first-in-human clinical trials.
Director of Cell Manufacturing, Program for Advanced Cell Therapy (PACT)
Currently Recruiting: As Director of Cellular Manufacturing, the successful candidate will be responsible for all administrative operations, quality assurance, and the development and implementation of all experimental cell-processing procedures in the UW Healthcare Cellular Therapy and Advanced Cellular Therapy Processing Laboratories, including compliance with FDA, FACT, AABB, and all other applicable regulations. The candidate will work in conjunction with the Medical Director of the Cell Therapy Laboratory to assure coordination with all aspects of the clinical service line Cell Therapy and Stem Cell Therapy Clinical Programs.
We are searching for an individual currently working in the cellular manufacturing industry, who has the following qualifications: the ability to manage multiple priorities, develop and manage budgets, problem-solve independently and make decisions, knowledge of laboratory operations and equipment and extensive knowledge of FACT and FDA PHS 351 and 361 guidelines. The starting salary will be based on the selected candidate’s qualifications.
If you or someone you know would be interested in this position, more information can be found in the attached flyer or on the University of Wisconsin jobs website at jobs.wisc.edu under PVL 98026.
Associate Director of R&D, Program for Advanced Cell Therapy (PACT)
Dr. Pennati has been with the University of Wisconsin – Madison since September 2016, when he transferred from Emory University, Atlanta, Georgia. Prior to coming to UW Madison, he worked in Dr. Galipeau’s laboratory for five years. Dr. Pennati completed a M.Sc. in Molecular Biology and a Ph.D. in Molecular Cell Biology at the University of Milan, Italy. Before joining the Galipeau lab, Dr. Pennati worked as a postdoctoral fellow with Dr. Giovanni Gadda at Georgia State University, in Atlanta, Georgia, in mechanistic enzymology of flavin-dependent enzymes. His work in Dr. Galipeau’s lab has included investigating the role of novel engineered fusion cytokines as part of cancer vaccine and cellular immunotherapy strategies. Current studies are aimed at defining the expansion and use of regulatory B cells in the treatment of different autoimmune ailments. With more than a decade of laboratory experience, Dr. Pennati leads translating cell-based research projects into clinical investigations by developing, standardized and establishing cellular processing protocols for use in cellular therapies.
Crystal Weinberger, MBA
A native of Wisconsin, Crystal graduated from the University of Wisconsin – Madison in 2004 with Bachelor’s degrees in Journalism and Political Science. She completed her Master’s in Business Administration in 2013 from the Carlson School of Management at the University of Minnesota. Her professional experience includes over 15 years of administrative service in the fields of healthcare, nonprofit management and academic medicine.