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Program for Advanced Cell Therapy
Integrated personalized cell technologies for improving health outcomes in children and adults
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New Phase I clinical trial protocol submitted to FDA to treat subjects with xerostomia after XRT for Head and Neck Cancer using “fresh” interferon-γ activated MSCs at UW Health

Posted on January 10, 2023

A new clinical trial protocol to be covered under an investigator-sponsored IND held by UW Program for Advanced for Advanced Cell Therapy was submitted to the FDA this week. Randall Kimple MD, PhD, UW Associate …

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UW PACT connects with FDA CATT to advance novel UW-Madison T-cell CRISPR methodology.

Posted on December 14, 2022

UW Program for Advanced Cell Therapy connects with FDA CBER Advanced Technologies Team (CATT) to advance clinical development of novel University of Wisconsin-Madison T-cell CRISPR methodology. Ross Meyers, Director of Cell Manufacturing of UW Program for Advanced Cell Therapy (PACT) …

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UW Program for Advanced Cell Therapy Director of R&D secures membership to UW Carbone Cancer Center

Posted on November 22, 2022

On November 16 2022, Andrea Pennati secured associate membership within the UW Carbone Cancer Center in the UW School of Medicine and Public Health. He has been appointed as a member of the UWCCC’s Developmental Therapeutics Program where innovations in …

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PACT Intern Completes MS in Applied Drug Development – joins manufacturing team

Posted on November 16, 2022

Xingyi Tang completed her Master of Science in the University of Wisconsin-Madison, School of Pharmacy Applied Drug Development program. Ms. Tang chose to complete the internship portion of her requirements in the UW Program for Advanced Cell Therapy. …

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Pilot Study of autologous MSCs for Radiation-Induced Xerostomia (Dry Mouth) in Head and Neck Cancer Patients Completed

Posted on November 13, 2022

The UW Program for Advanced Cell Therapy has completed enrollment for the pilot MARSH (Marrow-derived Autologous Stromal cells for the Restauration of Salivary Hypofunction) clinical trial. Six patients with radiation-induced Xerostomia (Dry Mouth) were treated in the …

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PACT Adds New Member to the cGMP Manufacturing Team!

Posted on November 13, 2022

The UW Program for Advanced Cell Therapy welcomes Jessica Murphy, BS, MLS (ASCP) as our new Process Development and Manufacturing Scientist. Ms. Murphy comes to us from the Center for Regenerative Medicine; Immune, Progenitor and Cell Therapy (IMPACT) …

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UW PACT submits Annual Report to FDA CBER for Viral-Specific Cell therapy IND

Posted on November 13, 2022

The Annual Report for the IND covering a University of Wisconsin (UW) clinical trial evaluating the safety of donor Viral-Specific T cells against CMV (cytomegalovirus) infection was submitted to the FDA CBER this week. This …

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THE FUTURE OF CELL THERAPY: NOVEL STUDY TESTS TREATMENT FOR RADIATION-INDUCED DRY MOUTH

Posted on June 19, 2022

For certain side effects of complex and lifesaving medical procedures, care teams can be left with limited and risky treatment options, but a program at UW Health is changing that using patients’ own cells as “living …

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PACT Director named one of Medicine Maker’s 2022 top 10 influential people in advanced medicine.

Posted on May 27, 2022

Don and Marilyn Anderson Professor of Oncology and Associate Dean for Therapeutics Development, University of Wisconsin in Madison, US Galipeau is the president-elect of the International Society for Cell Therapy and the director of the …

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PACT well represented at ISCT Annual Meeting

Posted on May 27, 2022

Several members of PACT’s staff recently attended the 2022 Annual Meeting of the International Society for Cell & Gene Therapy, May 4-7, 2022, in San Francisco, CA. From bench research to cell manufacturing, many aspects …

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